MalnutritiondiagnosedbycontrollingnutritionstatusisanegativepredictoroflifeprognosisinaorticarchaneurysmpatientstreatedwiththoracicendovascularaneurysmrepairVascularresearch-articleEarlyRecent,Aug25,./本文由“天纳”临床学术信息人工智能系统自动翻译ObjectivesControllingNutritionalStatus(CONUT)isausefulscreeningtoolformalnutritioninpatientswithvariousdiseases;however,howCONUT-diagnosedmalnutritionaffectspatientswithaorticarchaneurysmisunknown.ThisstudyaimedtorevealtheutilityofCONUTfordetectingthepatientswithhigh-riskaorticarchaneurysmwithmalnutrition.控制营养状况(conut)是各种疾病患者营养不良的一种有用的筛查工具;然而,conut诊断的营养不良如何影响主动脉弓瘤患者尚不清楚。本研究旨在揭示conut对营养不良高危主动脉弓瘤的诊断价值。MethodsSixtypatientstreatedforaorticarchaneurysmswithelectivethoracicendovascularaneurysmrepairfromtowereretrospectivelyanalyzedatasingleinstitution.PreoperativenutritionstatuswasevaluatedbyCONUT,andaCONUTscore≥3wasdefinedasmalnutrition.Theinfluenceofmalnutritiononthepatients’overallsurvival,aneurysm-relateddeath-freerates,andprevalenceofre-interventionswerealsoanalyzed.回顾性分析了年至年接受选择性胸内动脉瘤修补术治疗的60例主动脉弓瘤患者。术前营养状况用conut进行评估,conut评分≥3为营养不良。还分析了营养不良对患者总生存率、动脉瘤相关的无死亡率和再干预率的影响。ResultsTwenty-threepatientswerediagnosedwithmalnutrition.Overallsurvivalwassignificantlylowerinthemalnutritiongroup(P?=?0.).ThemultivariateCoxproportionalhazardanalysisrevealedthatage(P??0.)andmalnutrition(P?=?0.)werenegativepredictorsofoverallsurvival.Conversely,thetwogroupsdidnotdiffersignificantlyinaneurysm-relateddeath-freerates(P?=?0.)andtheprevalenceofre-interventions(P?=?0.).23名患者被诊断为营养不良。营养不良组的总生存率明显较低(p=0.)。多变量Cox比例风险分析显示年龄(p0.)和营养不良(p=0.)是总生存率的负预测因子。相反,两组在动脉瘤相关的无死亡率(p=0.)和再干预的发生率(p=0.)上没有显著差异。ConclusionsMalnutritiondiagnosedbyCONUTaswellasageisanegativepredictorofsurvivalprognosisinpatientswithaorticarchaneurysm.Conut诊断的营养不良和年龄是主动脉弓瘤患者生存预后的负预测因素。References1.Kim,DH,Kim,CA,Placide,S,et?al.Preoperativefrailtyassessmentandout
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